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PKAN

PKAN (pantothenate kinase-associated neurodegeneration) is the most common form of NBIA. Based on the age of onset and rate of progression, individuals with PKAN may be classified as having classic or atypical forms. However, as we learn more about PKAN, we have found that some people fall between these 2 categories. In other words, there is a broad spectrum of symptoms.

Classic PKAN
The symptoms of classic PKAN usually start to appear before age 6, on average around age 3…

Atypical PKAN
The symptoms of atypical PKAN are more variable than those of classic PKAN and appear at a later age…

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